There are many case studies about social media and other campaigns gone horribly wrong because they pissed off some group or another. Motrin and mommy bloggers is one that immediately comes to mind.
Well, Nissan has dived right in there, too with this commercial spot: http://www.youtube.com/watch?v=ycGoucHWIjc
What idiot in their ad agency thought it would be a good idea to show a car intentionally hitting, and likely killing, a motorcyclist? Even presented in a video-game style, it’s still irresponsible and likely to piss off the millions of motorcyclists in this country.
Moral of the story: Do not sell to one group at the expense of another. And don’t assume that stylizing the death of any group of people makes it okay.